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Big 12 Matchups
| Big 12 program | Record | Series |
|---|---|---|
| 8-37 | USC leads | |
| 14-26 | USC leads | |
| 2-3 | USC leads | |
| 2-2 | Series level | |
| 0-17 | USC leads | |
| 0-3 | USC leads | |
| 1-0 | Kansas leads | |
| 2-0 | Kansas State leads | |
| 4-2 | TCU leads | |
| 0-3 | USC leads | |
| 10-13 | USC leads | |
| 0-1 | USC leads | |
| Combined vs the Big 12Combined | 43-107 | USC leads |
Series on record since 1915, from the CollegeFootballData game log. Click any program for the full head-to-head and every meeting.
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How USC fares against the Big 12. In meetings on record since 1915 it leads 107-43 across 12 Big 12 series, with every series and how to watch below.
Whenever USC faces a Big 12 opponent, here is how to find the game.
Across 12 Big 12 series on record since 1915, USC holds a 107-43 edge on the Big 12. Its best matchup is Arizona, at 37-8. TCU has the upper hand, ahead 4-2 in that series. The tightest series is with BYU, 2-2 and level. USC has yet to beat Kansas and Kansas State. USC has never lost to Colorado, Houston, Texas Tech and West Virginia.
USC plays in the Big Ten (Power 4), so every meeting with a Big 12 program is a non-conference game. For the Big 12's own series, see the Big 12 rivalry pages. For every non-conference matchup in one place, use the matchups hub. For who leads the conference now, the Big 12 standings.
Written by
Conference Newsroom · Independent Big 12 coverage since 2026
The house desk of BIG12.CO - independent researchers tracking every Big 12 game, stat and storyline.
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USC Trojans plays in the Big Ten (Power 4), so it meets the Big 12 only in non-conference games. This page pulls every Big 12 series on record since 1915 into one view, USC against Arizona, Arizona State, Baylor, BYU, Colorado, Houston, Kansas, Kansas State, TCU, Texas Tech, Utah and West Virginia, with the combined record and links to each full head-to-head page. Combined, USC holds a 107-43 edge in these meetings. For the Big 12's own series see the rivalry pages, and for every opponent in one place, the matchups hub.
The Big 12 Report
Standings, the title race and one opinion on the Big 12. No filler.
Against Big 12 programs combined, the series on record since 1915 sits at 107-43 in USC's favour. Each head-to-head is broken down below.
Arizona, Arizona State, Baylor, BYU, Colorado, Houston, Kansas, Kansas State, TCU, Texas Tech, Utah and West Virginia. Each has its own head-to-head page with every meeting on record.